Luvox is also called Fluvoxamine
Indication
Luvox is a selective serotonin reuptake inhibitor (SSRI) used to treat obsessive-compulsive disorder (OCD). It may also be used to treat depression and other conditions as determined by your doctor.
Luvox is indicated for the treatment of obsessions and compulsions in patients with Obsessive Compulsive Disorder (OCD).
Obsessive Compulsive Disorder is characterized by recurrent and persistent ideas, thoughts, impulses or images (obsessions) that are ego-dystonic and/or repetitive, purposeful, and intentional behaviors (compulsions) that are recognized by the person as excessive or unreasonable.
For the symptomatic relief of depressive illness.
Precautions
During premarketing studies involving primarily depressed patients, hypomania or mania occurred in approximately 1% of patients treated with Luvox. Activation of mania/hypomania has also been reported in a small proportion of patients with major affective disorder who were treated with other marketed antidepressants. As with all antidepressants, Luvox maleate should be used cautiously in patients with a history of mania.
During premarketing studies, seizures were reported in 0.2% of Luvox -treated patients. Luvox maleate should be used cautiously in patients with a history of seizures. It should be discontinued in any patient who develops seizures.
The possibility of a suicide attempt is inherent in patients with depressive symptoms, whether these occur in primary depression or in association with another primary disorder such as OCD. Close supervision of high risk patients should accompany initial drug therapy. Prescriptions for Luvox maleate should be written for the smallest quantity of tablets consistent with good patient management in order to reduce the risk of overdose.
Since any psychoactive drug may impair judgement, thinking, or motor skills, patients should be cautioned about operating hazardous machinery, including automobiles, until they are certain that Luvox maleate therapy does not adversely affect their ability to engage in such activities.
Drug Interactions
Combined use of Luvox and MAO inhibitors is contraindicated. (See Warnings)
Do not take Luvox with terfenadine (Seldane), astemizole (Hismanal), or cisapride.
The potential for abuse, tolerance and physical dependence with Luvox has been studied in a nonhuman primate model. No evidence of dependency phenomena was found.
Generally, it is not possible to predict on the basis of preclinical or premarketing clinical experience the extent to which a CNS active drug will be misused, diverted, and/or abused once marketed. Consequently, physicians should carefully evaluate patients for a history of drug abuse and follow such patients closely, observing them for signs of fluvoxamine maleate misuse or abuse (i.e., development of tolerance, incrementation of dose, drug-seeking behavior).
Overdose
Symptoms of overdose of Luvox may include drowsiness, vomiting, diarrhea, and dizziness. Cardiac disturbances, liver function disturbances, convulsions and coma have also been reported.
Of the 354 cases of deliberate or accidental overdose involving Luvox reported, there were 19 deaths. Of the 19 deaths, 2 were in patients taking Luvox alone and the remaining 17 were in patients taking Luvox along with other drugs.
Precautions
- Follow the directions for using Luvox provided by your doctor.
- Store Luvox at room temperature, away from heat and light.
- Continue to take Luvox even if you feel better.
- If you miss a dose of >Luvox and you are taking 1 dose daily, take the missed dose if you remember the same day. Skip the missed dose if you do not remember until the next day. If you miss a dose of this medicine and you are taking more than 1 dose a day, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.
Do not share Luvox with others for whom it was not prescribed. Do not use Luvox for other health conditions. Keep Luvox out of the reach of children.
Disclaimer
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