Indication
Klipal belongs to a group of medicines called opioids. Opioids mimic the effects of naturally occurring pain reducing chemicals (endorphins). They combine with the opioid receptors in the brain and block the transmission of pain signals. Therefore, even though the cause of the pain may remain, less pain is actually felt.
Klipal is also sometimes used to treat diarrhoea because of it's constipating side effect, however this is not a recommended use of Klipal.
Klipal  is used in treatment of Cough, Mild to moderate pain.

Special precautions
Use with caution in
Asthma, Breathing problems, Decreased kidney function, Decreased liver function, Elderly people, Enlarged prostate gland (prostatic hypertrophy), Epilepsy, Hypothyroidism, Low blood pressure (hypotension).
Not to be used in
-Alcoholism
-Failure of function of part of the gut causing an obstruction (paralytic ileus)
-Head injury
-Increased pressure in the brain (raised intracranial pressure)
-Slow, shallow breathing (respiratory depression)
-Sudden asthma attack
Klipal should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using Klipal and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
- Klipal should be avoided in the third trimester of pregnancy, as it may affect the growth and development of the foetus or have harmful effects on foetal tissues. Seek medical advice from your doctor before using Klipal during any stage of pregnancy.
- Klipal passes into the breast milk, but at normal doses it is unlikely to harm the baby. Discuss with your doctor.

Label warnings
Klipal may cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink.

Side effects
Generally, Klipal side effects are as follows:
-Changes in mood
-Drowsiness
-Slow, shallow breathing (respiratory depression)
-Addiction to the medicine (dependence)
-Skin rashes
-Low blood pressure (hypotension)
-False perceptions of things that are not really there (hallucinations)
-Nausea and vomiting
-Constipation
The side effects listed above may not include all of the side effects of Klipal reported by the drug's manufacturer.
For more information about any other possible risks associated with Klipal, please read the information provided with the medicine or consult your doctor or pharmacist.

Drug Interactions
Klipal should not be taken with MAOI anti-depressants and for two weeks after they have been stopped.
When used together with ritonavir the blood level of Klipal may be increased.
When taken together with other drugs that have a sedative effect on the central nervous system, for example, alcohol, sleeping drugs, antidepressant drugs and antihistamines, drowsiness is likely to be increased.

Disclaimer
Always read informational leaflet before using medicine! The information can be changed and completed!!

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