Metamizol tablets are used for the treatment of pains of different origin and variable intensity: toothache, headache, arthralgia, neuralgia, myositis, mild to moderate visceral pain, high fever, not responding to other drugs. Metamizol injection is used in cases of acute and severe pain after operations and traumas, pain associated with neoplastic diseases, colicky pain etc.

Special precautions

• In view of the availability of safer pain relievers, avoid its use.
• Do not take it on an empty stomach; take it after meals.
• If you have hyperacidity or a peptic ulcer, avoid it.
• If symptoms of allergy in the form of skin rashes or asthma or symptoms of bone marrow depression such as sore throat or fever occur, stop the drug and consult the doctor.

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Side Effects
The most serious Metamizol side effect is on the bone marrow. Metamizol depresses the bone marrow activity which results in a decrease of protective white blood cells (agranulocytosis). This adverse effect occurs on the second or repeated exposure to the drug due to the formation of antibodies against it. Once these are formed, a subsequent use produces an allergic effect which can be fatal.
Other adverse effects include irritation of the stomach which is considerably more than that caused by aspirin. Prolonged use may prove to be toxic to the kidneys. Skin rashes and asthma can also be caused due to allergy.
Metamizol occasionally causes constipation. Drowsiness and dizziness occur when it is taken repeatedly to relieve moderate pain. Children are more susceptible to its adverse effects and it should be avoided in children below one year of age.

Precautions
1. Metamizol causes constipation. Take a high roughage diet while taking this drug.
2. Alcohol and anti-allergic drugs enhance its sedative effect. Avoid them while taking a formulation containing Metamizol.
3. Avoid its use in children, especially below one year of age, as they are more susceptible to its adverse effects.
4. It should be avoided by patients of bronchial asthma and other breathing problems.

Overdose
In case of overdose of Metamizol, immediately turn to medical center. If the victim has collapsed or is not breathing, call local emergency services.
Keep all appointments with your doctor. Do not let anyone else take your Metamizol prescription. Ask your pharmacist any questions you have about refilling your prescription.

Disclaimer
Always read informational leaflet before using medicine! The information can be changed and completed!!

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