Nortrilen is also called Aventyl, Pamelor, Nortrilen

Indication
Nortrilen relieves symptoms of depression.
The concurrent use of Nortrilen or other tricyclic antidepressants with a MAO inhibitor is contraindicated.
Cross sensitivity between Nortrilen and other dibenzazepines is a possibility. Nortriptyline is contraindicated during the acute recovery period after myocardial infarction.

Adverse Side Effects
Included in the following list are a few adverse reactions that have not been reported with this specific drug. However, the pharmacologic similarities among the tricyclic antidepressant drugs require that each of these reactions be considered when Nortrilen is administered.
Hypotension, hypertension, tachycardia, palpitation, myocardial infarction, arrhythmias, heart block, stroke.
Confusional states (especially in the elderly) with hallucinations, disorientation, delusions; anxiety, restlessness, agitation; insomnia, panic, nightmares; hypomania; exacerbation of psychosis.
Numbness, tingling, paresthesias of extremities; incoordination, ataxia, tremors; peripheral neuropathy, extrapyramidal symptoms; seizures, alteration of EEG patterns; tinnitus.
Dry mouth and, rarely, associated sublingual adenitis or gingivitis; blurred vision, disturbance of accommodation, mydriasis; constipation, paralytic ileus; urinary retention, delayed micturition, dilation of the urinary tract.
Skin rash, petechiae, urticaria, itching, photosensitization (avoid excessive exposure to sunlight); edema (general or of face and tongue), drug fever, cross-sensitivity with other tricyclic drugs.
Nausea and vomiting, anorexia, epigastric distress, diarrhea; peculiar taste, stomatitis, abdominal cramps, black tongue, constipation, paralytic ileus.
Endocrine; gynecomastia in the male; breast enlargement and galactorrhea in the female; increased or decreased libido, impotence; testicular swelling; elevation or depression of blood sugar levels; syndrome of inappropriate ADH (antidiuretic hormone) secretion. Jaundice (simulating obstructive); altered liver function, hepatitis, and liver necrosis; weight gain or loss; perspiration; flushing; urinary frequency, nocturia; drowsiness, dizziness, weakness, fatigue; headache; parotid swelling; alopecia.
Though these are not indicative of addiction, abrupt cessation of treatment after prolonged therapy may produce nausea, headache, and malaise.

Overdose
Symptoms of overdose of Nortrilen may begin within several hours of oral ingestion.
Symptoms and signs may include blurred vision, confusion, restlessness, dizziness, hypothermia, hyperthermia, agitation, vomiting, hyperactive reflexes, dilated pupils, fever, rapid heart rate, decreased bowel sounds, dry mouth, inability to void, myoclonic jerks, seizures, respiratory depression, myoglobinuric renal failure, nystagmus, ataxia, dysarthria, choreoathetosis, coma, hypotension, and cardiac arrhythmias.
In managing overdose, consider the possibility of multiple Nortrilen overdose, interactions among drugs, and unusual drug kinetics in your patients. Protect the patient's airway and support ventilation and perfusion. Absorption of Nortrilen from the gastrointestinal tract may be decreased by giving activated charcoal, which, in many cases, is more effective than emesis or lavage; consider charcoal instead of or in addition to gastric emptying. Repeated doses of charcoal over time may hasten elimination of some drugs that have been absorbed.

Special precautions

Before taking Nortrilen,

• Tell your doctor and pharmacist if you are allergic to Nortrilen or any other medications.
• Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.
• Tell your doctor if you or anyone in your family has or has ever had depression, bipolar disorder (mood that changes from depressed to abnormally excited), or mania (frenzied, abnormally excited mood), or if you or anyone in your family has thought about or attempted suicide.
• Also tell your doctor if you drink large amounts of alcohol; if you have recently had a heart attack; and if you have or have ever had glaucoma; an enlarged prostate; difficulty urinating; seizures; an overactive thyroid gland (hyperthyroidism); diabetes; or liver, kidney, or heart disease.
• Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Nortrilen, call your doctor immediately.
• If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking Nortrilen.
• You should know that Nortrilen may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
• Remember that alcohol can add to the drowsiness caused by this medication.
• You should know that your mental health may change in unexpected ways, especially at the beginning of your treatment and any time that your dose is increased or decreased.

Do not buy Nortrilen and use Nortrilen purchased at shady pharmacies!

Keep all appointments with your doctor and the laboratory. Do not let anyone else take your prescription for Nortrilen.

Disclaimer
Always read informational leaflet before using medicine! The information can be changed and completed!!

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